Children’s Health

Scientists at St. Jude Children’s Research Hospital have revealed how the tumor suppressor gene PTEN plays a more important role in pediatric rhabdomyosarcoma than was previously appreciated. The research highlights a possible new treatment approach.The study appears today in Nature Communications. In this study, researchers showed that decreased expression of PTEN makes tumors more aggressive.
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A paper published in the journal Psychological Medicine confirms the existence of neurobiological alterations in early stages of life in minors exposed to maltreatment. The study’s first author is the researcher Laia Marqués-Feixa, from the Faculty of Biology, the Institute of Biomedicine of the University of Barcelona (IBUB) and the CIBER Mental Health (CIBERSAM), and
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In a systematic review, researchers assessed the diagnostic value of certain physical symptoms that children may display that could indicate a urinary tract infection. The team performed literature reviews of the most prominent medical research databases from inception until Jan. 20, 2020 for studies reporting specific diagnostic accuracy data for clinical signs and symptoms compared
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Adhering to a diet and exercise program to manage health can be a challenge for anyone. But maintaining a healthy weight may present unique challenges for young adults with inherent barriers such as cognitive impairment. A pilot study at the University of Cincinnati found that young adults with autism spectrum disorder (ASD) and intellectual disabilities
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Six stages of engagement in treatment of Attention-Deficit/Hyperactivity Disorder (ADHD) have been reported by researchers at Boston Medical Center based on a diverse study, inclusive of parents of predominantly racial and ethnic minority children with ADHD. Published in Pediatrics, this new framework has been informed by the experiences of parents throughout the various stages that
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Eighteen months into the covid-19 pandemic, with the delta variant fueling a massive resurgence of disease, many hospitals are hitting a heartbreaking new low. They’re now losing babies to the coronavirus. The first reported covid-related death of a newborn occurred in Orange County, Florida, and an infant has died in Mississippi. Merced County in California
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While many parents and caregivers involved in the child welfare system suffered trauma as children, new research suggests that those with substance misuse issues as adults may have had particularly difficult childhoods. The study found that scores assessing childhood trauma exposure among adults with substance misuse issues were 24% higher than previous estimates for other
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Albert Einstein College of Medicine has received a five-year, $5 million grant from the National Institutes of Health (NIH) to support the Rose F. Kennedy Intellectual and Developmental Disabilities Research Center (RFK IDDRC), which has been at the forefront of research on normal and abnormal brain development for more than 50 years. The funding will
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Over the course of the pandemic, researchers nationwide noticed differences in COVID-19 disease between children and adults. While risk factors for hospitalization and poor outcomes are well documented in adults, less is known about the clinical factors associated with COVID disease severity in children. In an effort to aid mitigation strategies for children who are
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The initial period of the coronavirus disease 2019 (COVID-19) pandemic did not seriously affect children partly due to their relative isolation from sources of infection via school closures. However, the delta variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that is currently spreading has affected children more than that initial period. Study: The
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Epigenetic aging — derived from the molecular mechanisms governing gene regulation — could serve as a promising biomarker for measuring long-term cardiovascular health and disease risk, according to a Northwestern Medicine study published in the journal Circulation Research. Epigenetic aging represents a novel measure of biological age — or how old the body is physiologically,
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Patients with intellectual and developmental disabilities (IDD) are three times more likely to die from COVID-19 than the general population. Their heightened risk is due to a variety of causes: pre-existing health conditions, such as respiratory problems or obesity; increased likelihood of living in group homes, taking shared transportation, and being exposed to people outside
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An important new article published in the Clinical Medicine Journal discusses pregnancy complicated with coronavirus disease 2019 (COVID-19). This article provides an overview of what is currently known about this condition and current recommendations. COVID-19, which is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), first emerged in Wuhan, China at the end
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Researchers in the United States have warned that as of July 15th this year (2021), the level of population immunity against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19) – may still have been insufficient to contain infection outbreaks and safely return to pre-pandemic social behavior. As
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Hospitalized COVID-19 patients are substantially more likely to harbor autoantibodies -;antibodies directed at their own tissues or at substances their immune cells secrete into the blood -; than people without COVID-19, according to a new study. Autoantibodies can be early harbingers of full-blown autoimmune disease. If you get sick enough from COVID-19 to end up
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